Diagnostic Yield of Small Bowel Videocapsule Endoscopy in Patients with Iron Deficiency Anemia. A Systematic Review and meta-analysis.
J Clin Gastroenterol
; 2024 Jan 17.
Article
in En
| MEDLINE
| ID: mdl-38227849
ABSTRACT
BACKGROUND AND AIM:
Gastrointestinal (GI) bleeding or malabsorption represents the most frequent aetiologies of iron deficiency anemia (IDA). The cause of IDA remains undetermined in ~10% to 20% of patients undergoing upper and lower GI endoscopies. In this scenario, a small bowel examination with videocapsule endoscopy (VCE) is recommended. We performed a systematic review with meta-analysis to evaluate the diagnostic yield of VCE in patients with IDA without overt bleeding, assessing the prevalence of either any lesion or lesions at high potential of bleeding. MATERIALS ANDMETHODS:
A computerized literature search was performed using relevant keywords to identify all the pertinent articles published until March 2023.RESULTS:
Twelve studies with a total of 1703 IDA patients (Males 47%; age range 19-92 y) were included in this systematic review. The diagnostic yield of VCE for overall lesions in the small bowel was 61% (95% CI=44-77; 95 CI=97.2-98.1; I2=97.7%). When analyzing only small bowel lesions likely responsible of IDA, the diagnostic yield was 40% (95% CI=27-53; 95% CI=95.3-97; I2=96.3%).CONCLUSION:
VCE plays a relevant role in the diagnostic work-up of patients with IDA without overt bleeding with a satisfactory diagnostic yield.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Diagnostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Language:
En
Journal:
J Clin Gastroenterol
Year:
2024
Document type:
Article
Country of publication:
United States