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Candida auris-associated hospitalizations and outbreaks, China, 2018-2023.
Bing, Jian; Du, Han; Guo, Penghao; Hu, Tianren; Xiao, Meng; Lu, Sha; Nobile, Clarissa J; Chu, Haiqing; Huang, Guanghua.
Affiliation
  • Bing J; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People's Republic of China.
  • Du H; Department of Infectious Diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity, State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, People's Republic of China.
  • Guo P; Department of Infectious Diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity, State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, People's Republic of China.
  • Hu T; Department of Clinical Laboratory, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
  • Xiao M; Department of Infectious Diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity, State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, People's Republic of China.
  • Lu S; Department of Laboratory Medicine, Sate Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
  • Nobile CJ; Department of Dermatology and Venereology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
  • Chu H; Department of Molecular and Cell Biology, University of California, Merced, Merced, USA.
  • Huang G; Health Sciences Research Institute, University of California, Merced, Merced, USA.
Emerg Microbes Infect ; 13(1): 2302843, 2024 Dec.
Article in En | MEDLINE | ID: mdl-38238874
ABSTRACT
The emerging human fungal pathogen Candida auris has become a serious threat to public health. This pathogen has spread to 10 provinces in China as of December 2023. Here we describe 312 C. auris-associated hospitalizations and 4 outbreaks in healthcare settings in China from 2018 to 2023. Three genetic clades of C. auris have been identified during this period. Molecular epidemiological analyses indicate that C. auris has been introduced and local transmission has occurred in multiple instances in China. Most C. auris isolated from China (98.7%) exhibited resistance to fluconazole, while only a small subset of strains were resistant to amphotericin B (4.2%) and caspofungin (2.2%).
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candidiasis / Antifungal Agents Type of study: Risk_factors_studies Limits: Humans Country/Region as subject: Asia Language: En Journal: Emerg Microbes Infect Year: 2024 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candidiasis / Antifungal Agents Type of study: Risk_factors_studies Limits: Humans Country/Region as subject: Asia Language: En Journal: Emerg Microbes Infect Year: 2024 Document type: Article