Residual Immunity from Smallpox Vaccination and Possible Protection from Mpox, China.

Huang, Yu; Guo, Li; Li, Yanan; Ren, Lili; Nie, Jiqin; Xu, Fengwen; Huang, Tingxuan; Zhong, Jingchuan; Fan, Zhangling; Zhang, Yin; Xie, Yu; Zhang, Qiao; Mei, Shan; Xiao, Yan; Wang, Xinming; Xu, Liuhui; Guo, Fei; Wang, Jianwei

Huang, Yu; Guo, Li; Li, Yanan; Ren, Lili; Nie, Jiqin; Xu, Fengwen; Huang, Tingxuan; Zhong, Jingchuan; Fan, Zhangling; Zhang, Yin; Xie, Yu; Zhang, Qiao; Mei, Shan; Xiao, Yan; Wang, Xinming; Xu, Liuhui; Guo, Fei; Wang, Jianwei.

Emerg Infect Dis ; 30(2): 321-324, 2024 Feb.

Article in En | MEDLINE | ID: mdl-38270156

ABSTRACT

ABSTRACT

Among persons born in China before 1980 and tested for vaccinia virus Tiantan strain (VVT), 28.7% (137/478) had neutralizing antibodies, 71.4% (25/35) had memory B-cell responses, and 65.7% (23/35) had memory T-cell responses to VVT. Because of cross-immunity between the viruses, these findings can help guide mpox vaccination strategies in China.

Subject(s)

Mpox (monkeypox); Smallpox; Humans; Smallpox/prevention & control; Vaccination; Antibodies, Neutralizing; China/epidemiology; Vaccinia virus

Key words

China; memory B cell; memory T cell; monkeypox; mpox; neutralizing antibodies; smallpox; vaccine-preventable diseases; vaccinia virus; viruses

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smallpox / Mpox (monkeypox) Limits: Humans Country/Region as subject: Asia Language: En Journal: Emerg Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2024 Document type: Article Country of publication: United States

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