Hospital-based screening outperforms primary care screening as a means of achieving hepatitis C virus micro-elimination.
Infect Dis Now
; 54(2): 104855, 2024 Mar.
Article
in En
| MEDLINE
| ID: mdl-38309646
ABSTRACT
AIM:
To assess the respective performances of a HCV screening program in a hospital setting and a HCV screening model applied concomitantly in a primary care centre.METHODS:
Adult patients consecutively admitted to hospital for ambulatory surgery were screened for anti-HCV antibodies (hospital screening cohort, HPSC), as were patients receiving blood tests for medical reasons in a primary care centre (primary care screening cohort, PCSC). Serum anti-HCV and HCV RNA levels were tested by ELISA and real-time PCR, respectively.RESULTS:
Seroprevalence of HCV infection was 2.2 % in the HPSC and 1.4 % in the PCSC (p = 0.044). All viraemic patients (0.2 % in HPSC and 0.1 % in PCSC) were treated with direct-acting antivirals and 85.7 % experienced a sustained virological response.CONCLUSIONS:
Hospital-based HCV screening outperformed primary care-centered screening, significantly increasing HCV case findings.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hepatitis C
/
Hepatitis C, Chronic
Type of study:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Adult
/
Humans
Language:
En
Journal:
Infect Dis Now
Year:
2024
Document type:
Article
Affiliation country:
Spain