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New Iridoids and Acyclic Monoterpenoids from the Roots and Rhizomes of Valeriana officinalis var. latifolia.
Liu, Jia-Jin; Wang, Li-Zhong; Duan, Yuan-Ting; Liu, Dan; Li, Hong-Mei; Li, Rong-Tao.
Affiliation
  • Liu JJ; Faculty of Life Science and Technology, Kunming University of Science and Technology, 650500, Kunming, Yunnan, P. R. China.
  • Wang LZ; Faculty of Life Science and Technology, Kunming University of Science and Technology, 650500, Kunming, Yunnan, P. R. China.
  • Duan YT; Faculty of Life Science and Technology, Kunming University of Science and Technology, 650500, Kunming, Yunnan, P. R. China.
  • Liu D; Faculty of Life Science and Technology, Kunming University of Science and Technology, 650500, Kunming, Yunnan, P. R. China.
  • Li HM; Faculty of Life Science and Technology, Kunming University of Science and Technology, 650500, Kunming, Yunnan, P. R. China.
  • Li RT; Faculty of Life Science and Technology, Kunming University of Science and Technology, 650500, Kunming, Yunnan, P. R. China.
Chem Biodivers ; 21(2): e202301949, 2024 Feb.
Article in En | MEDLINE | ID: mdl-38326086
ABSTRACT
Five new iridoids, valeralides A-E (1-5), two new acyclic monoterpenoids, valeralides F (6) and G (7), together with two known iridoids (8 and 9), were isolated from the roots and rhizomes of Valeriana officinalis var. latifolia. Their structures were elucidated based on 1D and 2D NMR, as well as HR-ESI-MS spectroscopic data. The absolute configuration of compounds 1-4 were elucidated based on electronic circular dichroism (ECD) calculation. In addition, all the isolates were evaluated for their inhibition on nitric oxide production, cytotoxicity and anti-influenza A virus activity.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Valerian / Rhizome Language: En Journal: Chem Biodivers Journal subject: BIOQUIMICA / QUIMICA Year: 2024 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Valerian / Rhizome Language: En Journal: Chem Biodivers Journal subject: BIOQUIMICA / QUIMICA Year: 2024 Document type: Article