The impact of the COVID-19 pandemic on alcohol use disorder symptoms: Testing interactions with polygenic risk.
J Am Coll Health
; : 1-6, 2024 Feb 08.
Article
in En
| MEDLINE
| ID: mdl-38329837
ABSTRACT
Objective:
The purpose of this study was to test whether COVID impact interacts with genetic risk (polygenic risk score/PRS) to predict alcohol use disorder (AUD) symptoms.Method:
Participants were n = 455 college students (79.6% female, 51% European Ancestry/EA, 24% African Ancestry/AFR, 25% Americas Ancestry/AMER) from a longitudinal study during the initial stage (March-May 2020) of the pandemic. Path models allowed for the examination of PRS and previously identified COVID-19 impact constructs.Results:
There was a main effect of the AUD PRS on AUD symptoms within the EA group (ß .165, p < .01). Additionally, food/housing insecurity was predictive in the AMER group (ß.295, p < .05), and greater increases in substance use were associated with AUD symptoms for EA (ß.459, p < .001) and AMER groups (ß.468, p < .001).Conclusions:
Greater food/housing instability and increases in substance use, as well higher scores on PRS are associated with more AUD symptoms for some ancestral groups within this college sample.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Language:
En
Journal:
J Am Coll Health
Year:
2024
Document type:
Article
Affiliation country:
United States