Protocol for analyzing emergence dynamics of diabetes with obesity using numerical continuation and bifurcation analysis.
STAR Protoc
; 5(1): 102880, 2024 Mar 15.
Article
in En
| MEDLINE
| ID: mdl-38349789
ABSTRACT
Type 2 diabetes (T2D) is a multifactorial disease that slowly and inconspicuously progresses over years. Here, we present a protocol for analyzing slow progression dynamics of T2D with obesity. We describe steps for using software to exploit the differences between the timescales of the metabolic variables and using numerical continuation and bifurcation analysis. We detail procedures to analyze bi-stable system dynamics and identify the thresholds that separate healthy and diabetic states. For complete details on the use and execution of this protocol, please refer to Yildirim et al. (2023).1.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Diabetes Mellitus, Type 2
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
STAR Protoc
Year:
2024
Document type:
Article
Country of publication:
United States