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Environmental and Health Impacts of Graphene and Other Two-Dimensional Materials: A Graphene Flagship Perspective.
Lin, Hazel; Buerki-Thurnherr, Tina; Kaur, Jasreen; Wick, Peter; Pelin, Marco; Tubaro, Aurelia; Carniel, Fabio Candotto; Tretiach, Mauro; Flahaut, Emmanuel; Iglesias, Daniel; Vázquez, Ester; Cellot, Giada; Ballerini, Laura; Castagnola, Valentina; Benfenati, Fabio; Armirotti, Andrea; Sallustrau, Antoine; Taran, Frédéric; Keck, Mathilde; Bussy, Cyrill; Vranic, Sandra; Kostarelos, Kostas; Connolly, Mona; Navas, José Maria; Mouchet, Florence; Gauthier, Laury; Baker, James; Suarez-Merino, Blanca; Kanerva, Tomi; Prato, Maurizio; Fadeel, Bengt; Bianco, Alberto.
Affiliation
  • Lin H; CNRS, UPR3572, Immunology, Immunopathology and Therapeutic Chemistry, ISIS, University of Strasbourg, 67000 Strasbourg, France.
  • Buerki-Thurnherr T; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Particles-Biology Interactions, 9014 St. Gallen, Switzerland.
  • Kaur J; Nanosafety & Nanomedicine Laboratory, Institute of Environmental Medicine, Karolinska Institutet, 177 77 Stockholm, Sweden.
  • Wick P; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Particles-Biology Interactions, 9014 St. Gallen, Switzerland.
  • Pelin M; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
  • Tubaro A; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
  • Carniel FC; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
  • Tretiach M; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
  • Flahaut E; CIRIMAT, Université de Toulouse, CNRS, INPT, UPS, 31062 Toulouse CEDEX 9, France.
  • Iglesias D; Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha (UCLM), 13071 Ciudad Real, Spain.
  • Vázquez E; Instituto Regional de Investigación Científica Aplicada (IRICA), Universidad de Castilla-La Mancha (UCLM), 13071 Ciudad Real, Spain.
  • Cellot G; Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha (UCLM), 13071 Ciudad Real, Spain.
  • Ballerini L; Instituto Regional de Investigación Científica Aplicada (IRICA), Universidad de Castilla-La Mancha (UCLM), 13071 Ciudad Real, Spain.
  • Castagnola V; International School for Advanced Studies (SISSA), 34136 Trieste, Italy.
  • Benfenati F; International School for Advanced Studies (SISSA), 34136 Trieste, Italy.
  • Armirotti A; Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, 16132 Genova, Italy.
  • Sallustrau A; IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
  • Taran F; Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, 16132 Genova, Italy.
  • Keck M; IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
  • Bussy C; Analytical Chemistry Facility, Istituto Italiano di Tecnologia, 16163 Genoa, Italy.
  • Vranic S; Département Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SIMoS, Gif-sur-Yvette 91191, France.
  • Kostarelos K; Département Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SIMoS, Gif-sur-Yvette 91191, France.
  • Connolly M; Département Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SIMoS, Gif-sur-Yvette 91191, France.
  • Navas JM; Nanomedicine Lab, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, National Graphene Institute, Manchester M13 9PT, United Kingdom.
  • Mouchet F; Nanomedicine Lab, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, National Graphene Institute, Manchester M13 9PT, United Kingdom.
  • Gauthier L; Nanomedicine Lab, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, National Graphene Institute, Manchester M13 9PT, United Kingdom.
  • Baker J; Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), CSIC, Carretera de la Coruña Km 7,5, E-28040 Madrid, Spain.
  • Suarez-Merino B; Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), CSIC, Carretera de la Coruña Km 7,5, E-28040 Madrid, Spain.
  • Kanerva T; Laboratoire Ecologie Fonctionnelle et Environnement, Université de Toulouse, CNRS, INPT, UPS, 31000 Toulouse, France.
  • Prato M; Laboratoire Ecologie Fonctionnelle et Environnement, Université de Toulouse, CNRS, INPT, UPS, 31000 Toulouse, France.
  • Fadeel B; TEMAS Solutions GmbH, 5212 Hausen, Switzerland.
  • Bianco A; TEMAS Solutions GmbH, 5212 Hausen, Switzerland.
ACS Nano ; 18(8): 6038-6094, 2024 Feb 27.
Article in En | MEDLINE | ID: mdl-38350010
ABSTRACT
Two-dimensional (2D) materials have attracted tremendous interest ever since the isolation of atomically thin sheets of graphene in 2004 due to the specific and versatile properties of these materials. However, the increasing production and use of 2D materials necessitate a thorough evaluation of the potential impact on human health and the environment. Furthermore, harmonized test protocols are needed with which to assess the safety of 2D materials. The Graphene Flagship project (2013-2023), funded by the European Commission, addressed the identification of the possible hazard of graphene-based materials as well as emerging 2D materials including transition metal dichalcogenides, hexagonal boron nitride, and others. Additionally, so-called green chemistry approaches were explored to achieve the goal of a safe and sustainable production and use of this fascinating family of nanomaterials. The present review provides a compact survey of the findings and the lessons learned in the Graphene Flagship.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: ACS Nano Year: 2024 Document type: Article Affiliation country: France Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: ACS Nano Year: 2024 Document type: Article Affiliation country: France Country of publication: United States