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Status check: next-generation sequencing for infectious-disease diagnostics.
Rodino, Kyle G; Simner, Patricia J.
Affiliation
  • Rodino KG; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Simner PJ; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
J Clin Invest ; 134(4)2024 Feb 15.
Article in En | MEDLINE | ID: mdl-38357923
ABSTRACT
Next-generation sequencing (NGS) applications for the diagnostics of infectious diseases has demonstrated great potential with three distinct approaches whole-genome sequencing (WGS), targeted NGS (tNGS), and metagenomic NGS (mNGS, also known as clinical metagenomics). These approaches provide several advantages over traditional microbiologic methods, though challenges still exist.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Metagenomics / High-Throughput Nucleotide Sequencing Type of study: Diagnostic_studies Language: En Journal: J Clin Invest Year: 2024 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Metagenomics / High-Throughput Nucleotide Sequencing Type of study: Diagnostic_studies Language: En Journal: J Clin Invest Year: 2024 Document type: Article Affiliation country: United States