Predictive role of neutrophil-to-platelet ratio in futile recanalization of patients after endovascular therapy.
Biomark Med
; 18(4): 137-143, 2024 Feb.
Article
in En
| MEDLINE
| ID: mdl-38375795
ABSTRACT
Aim:
To explore the association between the neutrophil-to-platelet ratio (NPR) and futile recanalization (FR) in patients with acute ischemic stroke due to large vascular occlusions after endovascular therapy (EVT).Methods:
FR after EVT was defined as a poor 90-day prognosis (modified Rankin scale [mRS] score ≥3) despite successful reperfusion (modified thrombolysis in cerebral infarction grade 2b-3). Patients were divided into high NPR (>35; n = 115) and low NPR (≤35; n = 81) groups.Results:
The FR rate was significantly higher in the high NPR group than low NPR group (81.74 vs 55.56%; p = 0.000). NPR was independently associated with FR (odds ratio 2.107; 95% CI 1.017-4.364; p = 0.045).Conclusion:
High NPR was associated with the risk of FR in patients with acute ischemic stroke due to large vascular occlusions.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain Ischemia
/
Stroke
/
Endovascular Procedures
/
Ischemic Stroke
Limits:
Humans
Language:
En
Journal:
Biomark Med
Journal subject:
BIOQUIMICA
/
MEDICINA
Year:
2024
Document type:
Article
Affiliation country:
China