Generation of induced pluripotent stem cell line NIMHi010-A from dermal fibroblast cells of a healthy individual.
Stem Cell Res
; 76: 103355, 2024 Apr.
Article
in En
| MEDLINE
| ID: mdl-38412659
ABSTRACT
In this study, we have established human induced pluripotent stem cell (hiPSC) line, NIMHi010-A of a 42-year-old healthy donor. The iPSC line was generated from human dermal fibroblasts using Sendai viruses carrying reprogramming factors c-MYC, SOX2, KLF4, and OCT4 under a feeder-free culture system. The generated hiPSC line expressed typical pluripotency markers, displayed a normal karyotype, and demonstrated the potential to differentiate into the three germ layers. This hiPSC line will serve as a healthy control model for physiological processes and drug screening of Asian origin from Indian population.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Induced Pluripotent Stem Cells
Limits:
Adult
/
Humans
Language:
En
Journal:
Stem Cell Res
Year:
2024
Document type:
Article
Affiliation country:
India
Country of publication:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM