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Knuckle hyperpigmentation in a young male: A clinical sign of B12 deficiency not to be missed.
Singh, Harpreet; Subramanian, Arvind; Dibhar, Deba P; Suri, Vikas; Bhalla, Ashish.
Affiliation
  • Singh H; Department of Internal Medicine and Division of Clinical Infectious Diseases, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Subramanian A; Department of Internal Medicine and Division of Clinical Infectious Diseases, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Dibhar DP; Department of Internal Medicine and Division of Clinical Infectious Diseases, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Suri V; Department of Internal Medicine and Division of Clinical Infectious Diseases, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
  • Bhalla A; Department of Internal Medicine and Division of Clinical Infectious Diseases, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Trop Doct ; 54(3): 282-283, 2024 Jul.
Article in En | MEDLINE | ID: mdl-38419508
ABSTRACT
Vitamin B12 and folate deficiency are reversible causes of megaloblastic anemia. Strict vegetarians are at risk of megaloblastic anemia due to low cobalamin in their diet. Knuckle hyperpigmentation in patients with megaloblastic anemia is due to excess melanin synthesis in skin. Here we present a case of a young vegetarian male with megaloblastic anemia with knuckle hyperpigmentation managed successfully with intravenous followed by oral vitamin b12 and folate supplementation.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitamin B 12 / Vitamin B 12 Deficiency / Hyperpigmentation / Folic Acid / Anemia, Megaloblastic Limits: Adult / Humans / Male Language: En Journal: Trop Doct Year: 2024 Document type: Article Affiliation country: India Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitamin B 12 / Vitamin B 12 Deficiency / Hyperpigmentation / Folic Acid / Anemia, Megaloblastic Limits: Adult / Humans / Male Language: En Journal: Trop Doct Year: 2024 Document type: Article Affiliation country: India Country of publication: United kingdom