A tale of two pathways: Review of immune checkpoint inhibitors in DNA mismatch repair-deficient and microsatellite instability-high endometrial cancers.

Liu, Ying L; Weigelt, Britta

Liu, Ying L; Weigelt, Britta.

Affiliation

Liu YL; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Weigelt B; Department of Medicine, Weill Cornell Medical College, New York, New York, USA.

Cancer ; 130(10): 1733-1746, 2024 May 15.

Article in En | MEDLINE | ID: mdl-38422006

Subject(s)

DNA Mismatch Repair; Endometrial Neoplasms; Immune Checkpoint Inhibitors; Microsatellite Instability; Humans; Immune Checkpoint Inhibitors/therapeutic use; Endometrial Neoplasms/genetics; Endometrial Neoplasms/drug therapy; Female; DNA Mismatch Repair/genetics; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics; Colorectal Neoplasms, Hereditary Nonpolyposis/drug therapy; Tumor Microenvironment/genetics; Tumor Microenvironment/immunology

Key words

Lynch syndrome; MMRD mechanism; checkpoint inhibitors; endometrial cancer; genetic testing; microsatellite instability; mismatch repairdeficiency

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endometrial Neoplasms / Microsatellite Instability / DNA Mismatch Repair / Immune Checkpoint Inhibitors Limits: Female / Humans Language: En Journal: Cancer Year: 2024 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google