Navigating the terrain of neutrophil extracellular traps in severe malaria pathogenesis.
Trends Parasitol
; 40(4): 278-279, 2024 Apr.
Article
in En
| MEDLINE
| ID: mdl-38485580
ABSTRACT
Du, Ren, et al. recently showed in a Plasmodium berghei ANKA (PbA) experimental malaria model that phosphatase of regenerating liver 2 (PRL2) regulates neutrophil extracellular traps (NETs) in severe malaria (SM)-related acute lung injury (ALI). PRL2 deficiency caused SM with ALI in a mouse model by increasing NETs in pulmonary tissue; hydroxychloroquine (HCQ) may ameliorate this.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Acute Lung Injury
/
Extracellular Traps
/
Malaria
Limits:
Animals
Language:
En
Journal:
Trends Parasitol
Journal subject:
PARASITOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Australia