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Next-generation vaccines for tropical infectious diseases.
Allen, Tammy; Castellanos, Maria Eugenia; Giacomin, Paul; Karunaweera, Nadira D; Kupz, Andreas; Lol, Juan Carlos; Sharma, Dileep; Sikder, Suchandan; Tedla, Bemnet; van Eijk, Liza; Vojisavljevic, Danica; Zhao, Guangzu; Pai, Saparna.
Affiliation
  • Allen T; College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia.
  • Castellanos ME; College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia; Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia.
  • Giacomin P; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia.
  • Karunaweera ND; Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
  • Kupz A; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia.
  • Lol JC; Centro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
  • Sharma D; Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia; College of Medicine & Dentistry, James Cook University, Cairns, Australia; School of Health Sciences, College of Health Medicine and Wellbeing, The University of Newcastle, Ourimbah, Australia.
  • Sikder S; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia.
  • Tedla B; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia; Faculty of Health, Queensland University of Technology, Brisbane, Australia.
  • van Eijk L; Department of Psychology, James Cook University, Townsville, Australia.
  • Vojisavljevic D; College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia; Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia.
  • Zhao G; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia.
  • Pai S; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia. Electronic address: saparna.pai@jcu.edu.au.
Int J Infect Dis ; 143: 107014, 2024 Jun.
Article in En | MEDLINE | ID: mdl-38499058
ABSTRACT
Tropical infectious diseases inflict an unacceptable burden of disease on humans living in developing countries. Although anti-pathogenic drugs have been widely used, they carry a constant threat of selecting for resistance. Vaccines offer a promising means by which to enhance the global control of tropical infectious diseases; however, these have been difficult to develop, mostly because of the complex nature of the pathogen lifecycles. Here, we present recently developed vaccine candidates for five tropical infectious diseases in the form of a catalog that have either entered clinical trials or have been licensed for use. We deliberate on recently licensed dengue vaccines, provide evidence why combination vaccination could have a synergistic impact on schistosomiasis, critically appraise the value of typhoid conjugate vaccines, and discuss the potential of vaccines in the efforts to eliminate vivax malaria and hookworms.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dengue Limits: Humans Language: En Journal: Int J Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2024 Document type: Article Affiliation country: Australia
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Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dengue Limits: Humans Language: En Journal: Int J Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2024 Document type: Article Affiliation country: Australia