Pathophysiology-Based Management of Secondary Injuries and Insults in TBI.
Biomedicines
; 12(3)2024 Feb 26.
Article
in En
| MEDLINE
| ID: mdl-38540133
ABSTRACT
Traumatic Brain Injury (TBI) remains a leading cause of morbidity and mortality among all ages; despite the advances, understanding pathophysiological responses after TBI is still complex, involving multiple mechanisms. Previous reviews have focused on potential targets; however, the research on potential targets has continuously grown in the last five years, bringing even more alternatives and elucidating previous mechanisms. Knowing the key and updated pathophysiology concepts is vital for adequate management and better outcomes. This article reviews the underlying molecular mechanisms, the latest updates, and future directions for pathophysiology-based TBI management.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Biomedicines
Year:
2024
Document type:
Article
Affiliation country:
United States
Country of publication:
Switzerland