The paradox of platypnoea-orthodeoxia syndrome.
Intern Med J
; 54(4): 675-677, 2024 Apr.
Article
in En
| MEDLINE
| ID: mdl-38572793
ABSTRACT
Platypnoea-orthodeoxia is a rare clinical syndrome characterised by dyspnoea and oxygen desaturation in the upright position which improves when supine. It requires two components a sufficiently sized anatomical vascular defect (typically intra-cardiac or intra-pulmonary) combined with a functional component that promotes positional right-to-left shunting. We describe the rare occurrence of a patient with platypnoea-orthodeoxia syndrome (POS) because of a paradoxical shunt through a patent foramen ovale caused by a large right atrial line-associated thrombus in a male with metastatic oesophageal cancer undergoing chemotherapy. This case is a timely reminder to consider POS amongst differentials for hypoxia as it is often treatable if recognised.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Foramen Ovale, Patent
/
Platypnea Orthodeoxia Syndrome
Limits:
Humans
/
Male
Language:
En
Journal:
Intern Med J
/
Intern. med. j
/
Internal medicine journal
Journal subject:
MEDICINA INTERNA
Year:
2024
Document type:
Article
Affiliation country:
Australia
Country of publication:
Australia