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3-Methylcatechol mediates anti-fecundity effect by inhibiting estrogen-related receptor-induced glycolytic gene expression in Myzus persicae.
Park, Woo-Ram; Choi, Hueng-Sik; Moon, Jae-Hak; Kim, In-Seon; Kim, Don-Kyu.
Affiliation
  • Park WR; Host-Directed Antiviral Research Center, Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea.
  • Choi HS; Host-Directed Antiviral Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Republic of Korea. Electronic address: hsc@chonnam.ac.kr.
  • Moon JH; Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea. Electronic address: nutrmoon@jnu.ac.kr.
  • Kim IS; Department of Agricultural Chemistry, Institute of Environmentally Friendly Agriculture, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 61186, Republic of Korea. Electronic address: mindzero@jnu.ac.kr.
  • Kim DK; Host-Directed Antiviral Research Center, Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea. Electronic address: dkkim2@jnu.ac.kr.
Pestic Biochem Physiol ; 200: 105802, 2024 Mar.
Article in En | MEDLINE | ID: mdl-38582605
ABSTRACT
Aphids are a major problem in agriculture, horticulture, and forestry by feeding on leaves and stems, causing discoloration, leaf curling, yellowing, and stunted growth. Although urushiol, a phenolic compound containing a catechol structure, is known for its antioxidant and anticancer properties, using small molecules to control aphids via catechol-mediated mechanisms is poorly understood. In this study, we investigated the effects of 3-methylcatechol (3-MC) on Myzus persicae fecundity. Our results showed that treatment with 3-MC significantly reduced the intrinsic transcriptional activity of the aphid estrogen-related receptor (MpERR), which regulates the expression of glycolytic genes. Additionally, 3-MC treatment suppressed the promoter activity of MpERR-induced rate-limiting enzymes in glycolysis, such as phosphofructokinase and pyruvate kinase, by inhibiting MpERR binding. Finally, 3-MC also suppressed MpERR-induced glycolytic gene expression and reduced the number of offspring produced by viviparous female aphids. Overall, our findings suggest that 3-MC has the potential to be used as a new strategy for managing aphid populations by controlling their offspring production.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aphids Limits: Animals Language: En Journal: Pestic Biochem Physiol Year: 2024 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aphids Limits: Animals Language: En Journal: Pestic Biochem Physiol Year: 2024 Document type: Article Country of publication: United States