Absolute structure determination of Berkecoumarin by X-ray and electron diffraction.
Acta Crystallogr C Struct Chem
; 80(Pt 5): 143-147, 2024 May 01.
Article
in En
| MEDLINE
| ID: mdl-38598330
ABSTRACT
X-ray and electron diffraction methods independently identify the S-enantiomer of Berkecoumarin [systematic name (S)-8-hydroxy-3-(2-hydroxypropyl)-6-methoxy-2H-chromen-2-one]. Isolated from Berkeley Pit Lake Penicillium sp., Berkecoumarin is a natural product with a light-atom composition (C13H14O5) that challenges in-house absolute structure determination by anomalous scattering. This study further demonstrates the utility of dynamical refinement of electron-diffraction data for absolute structure determination.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Acta Crystallogr C Struct Chem
Year:
2024
Document type:
Article
Affiliation country:
United States