Characteristics of beta parapapillary atrophy in primary angle-closure suspect.
BMJ Open Ophthalmol
; 9(1)2024 Apr 15.
Article
in En
| MEDLINE
| ID: mdl-38626931
ABSTRACT
OBJECTIVE:
To investigate the characteristics of beta parapapillary atrophy (ß-PPA) in patients with primary angle-closure suspect (PACS). METHODS ANDANALYSIS:
In total, 215 and 259 eyes with PACS and non-PACS (NPACS), respectively, were enrolled in this observational, cross-sectional study. Stereoscopic fundus and optical coherence tomography images were used to characterise ß-PPA; the former was also used to measure the major ß-PPA parameters. Univariate and multiple logistic regression analyses were used to identify the factors correlated with the presence of ß-PPA and with ß-PPA parameters.RESULTS:
The ß-PPA occurrence rates were 48.80% and 44.40% in the PACS and NPACS groups, respectively, with no significant difference between groups. Compared with that in the NPACS group, the ß-PPA area was significantly larger (p=0.005) in the PACS group, but the angular extent and maximum radial length did not differ between groups (p=0.110 and 0.657, respectively) after adjusting for age and axial length. The presence of ß-PPA was associated with older age (OR 1.057, 95% CI 1.028 to 1.088, p<0.001) and larger disc area (OR 1.716, 95% CI 1.170 to 2.517, p=0.006). A larger ß-PPA area was associated with older age (p=0.014), greater vertical cup-to-disc ratio (p=0.028), larger disc area (p<0.001) and PACS diagnosis (p=0.035).CONCLUSION:
48.80% of participants with PACS had ß-PPA, which is slightly larger than NPACS. The area of ß-PPA was larger in PACS, while the angular extent and maximum radial length did not differ between groups.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Optic Disk
/
Eye Diseases, Hereditary
/
Optic Atrophy
/
Glaucoma, Open-Angle
Limits:
Humans
Language:
En
Journal:
BMJ Open Ophthalmol
Year:
2024
Document type:
Article
Affiliation country:
China