Quantification of the Bioactivity of Ethanolic Extract From Phoenix dactylifera.

ABSTRACT

AIM: This study aims to quantitatively assess the anti-inflammatory and antioxidant activities of the ethanolic extract of Phoenix dactylifera seeds. MATERIALS AND METHODS: Around 30 seeds of Phoenix dactylifera were collected, crushed, and powdered; 10 gm of powder was added to 100 ml of ethanolic extract and boiled for further analysis. Egg albumin denaturation assay and hydroxyl radical scavenging assay were done to evaluate the anti-inflammatory and antioxidant activity, respectively. An independent t-test was used to compare the anti-inflammatory and antioxidant potential of the ethanolic extract of Phoenix dactylifera using SPSS Statistics version 22.0 (IBM Corp. Released 2013. IBM SPSS Statistics for Windows, Version 22.0; Armonk, NY IBM Corp.), and values less than 0.05 are considered statistically significant. RESULTS: The seeds of Phoenix dactylifera have potent anti-inflammatory and antioxidant properties. Both anti-inflammatory and antioxidant properties improved with higher concentrations and were comparable to the control substances diclofenac sodium, vitamin E, and ascorbic acid, respectively. The most significant anti-inflammatory and antioxidant effect was observed at a dosage of 50 µL, with a p-value of 0.001. CONCLUSION: To conclude, we found that the ethanolic extract of Phoenix dactylifera has anti-inflammatory and antioxidant activity, which can further be used for the improvement of pharmaceuticals.