Dry eye rate and its relationship with disease stage in patients with primary hypertension: a cross-sectional study in Vietnam.
Int J Ophthalmol
; 17(4): 653-658, 2024.
Article
in En
| MEDLINE
| ID: mdl-38638268
ABSTRACT
AIM:
To determine the dry eye (DE) rate and its relationship with disease stage in patients with primary hypertension.METHODS:
A cross-sectional study included 432 patients with primary hypertension (with an equal number of patients in each group 144 in stage I, II, and III hypertension) and 144 healthy subjects as a control group. The Ocular Surface Disease Index (OSDI) and Schirmer I test without anesthetics were conducted on all 576 subjects. Subjects with OSDI scores <13 and Schirmer I values equal to or under 10 mm were diagnosed with DE.RESULTS:
The ratio of DE in hypertension patients was higher than in the control group (41.7% versus 18.8%; P<0.001). The proportion of patients with DE increased gradually according to the hypertension stage 27.1% in stage I, 40.3% in stage II, and 57.6% in stage III, P<0.001. Age, duration of hypertension, plasma urea, creatinine, and high-sensitivity C-reactive protein (CRP-hs) levels in hypertension patients with DE were higher than those without DE, P<0.001. Advanced age, a long duration of hypertension, diabetes mellitus, elevated plasma creatinine, and CRP-hs levels were independent factors associated with DE in primary hypertension patients, P<0.001.CONCLUSION:
DE is a common disorder associated with advanced age, a long duration of hypertension, diabetes mellitus, elevated plasma CRP-hs, and creatinine levels in patients with primary hypertension.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Int J Ophthalmol
Year:
2024
Document type:
Article
Affiliation country:
Vietnam
Country of publication:
China