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Successful haploidentical hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria with severe pancytopenia developed after long-term aplastic anemia treatment.
Sakurai, Kazuki; Saito, Kei; Hatta, Shunsuke; Katsuoka, Yuna; Meguro, Kuniaki; Yokoyama, Hisayuki; Izumi, Toru.
Affiliation
  • Sakurai K; Department of Hematology National Hospital Organization Sendai Medical Center Sendai Japan.
  • Saito K; Department of Hematology Tohoku University Hospital Sendai Japan.
  • Hatta S; Department of Hematology National Hospital Organization Sendai Medical Center Sendai Japan.
  • Katsuoka Y; Department of Hematology National Hospital Organization Sendai Medical Center Sendai Japan.
  • Meguro K; Department of Hematology National Hospital Organization Sendai Medical Center Sendai Japan.
  • Yokoyama H; Department of Hematology National Hospital Organization Sendai Medical Center Sendai Japan.
  • Izumi T; Department of Hematology National Hospital Organization Sendai Medical Center Sendai Japan.
Clin Case Rep ; 12(5): e8832, 2024 May.
Article in En | MEDLINE | ID: mdl-38681032
ABSTRACT
Haploidentical hematopoietic stem cell transplantation (HSCT) with posttransplant cyclophosphamide is an alternative treatment for aplastic anemia-paroxysmal nocturnal hemoglobinuria (PNH) syndrome with poor prognostic factors. Ravulizumab treatment for PNH before HSCT might have a beneficial effect.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Clin Case Rep Year: 2024 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Clin Case Rep Year: 2024 Document type: Article Country of publication: United kingdom