[Progress in the analysis of hemolysis and coagulation models for interventional micro-axial flow blood pumps].
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
; 41(2): 383-388, 2024 Apr 25.
Article
in Zh
| MEDLINE
| ID: mdl-38686421
ABSTRACT
Interventional micro-axial flow blood pump is widely used as an effective treatment for patients with cardiogenic shock. Hemolysis and coagulation are vital concerns in the clinical application of interventional micro-axial flow pumps. This paper reviewed hemolysis and coagulation models for micro-axial flow blood pumps. Firstly, the structural characteristics of commercial interventional micro-axial flow blood pumps and issues related to clinical applications were introduced. Then the basic mechanisms of hemolysis and coagulation were used to study the factors affecting erythrocyte damage and platelet activation in interventional micro-axial flow blood pumps, focusing on the current models of hemolysis and coagulation on different scales (macroscopic, mesoscopic, and microscopic). Since models at different scales have different perspectives on the study of hemolysis and coagulation, a comprehensive analysis combined with multi-scale models is required to fully consider the influence of complex factors of interventional pumps on hemolysis and coagulation.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Blood Coagulation
/
Heart-Assist Devices
/
Hemolysis
Limits:
Humans
Language:
Zh
Journal:
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Journal subject:
ENGENHARIA BIOMEDICA
Year:
2024
Document type:
Article