Nivolumab-associated immune-related filamentary keratitis.
BMJ Case Rep
; 17(4)2024 Apr 30.
Article
in En
| MEDLINE
| ID: mdl-38688575
ABSTRACT
A woman in her late 50s presented to the ophthalmology clinic having bilateral eye pain and discharge for the last month. Her medical history was significant for lung adenocarcinoma, for which she was being treated with nivolumab. Filamentary keratitis was evident at the slit-lamp examination. Regardless of ophthalmic reasons, nivolumab was suspended. Prednisolone ointment was started, with a complete remission. We present a case of steroid-responsive filamentary keratitis triggered by nivolumab. We aim to highlight the importance of prompt ophthalmology referral and the use of therapies targeting ocular surface inflammation in immune checkpoint inhibition therapy.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Nivolumab
/
Keratitis
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
BMJ Case Rep
Year:
2024
Document type:
Article
Affiliation country:
Portugal
Country of publication:
United kingdom