Causes and outcomes of non-chemotherapy induced neutropenic fever in hospitalized adults: An observational study.
Medicine (Baltimore)
; 103(18): e38060, 2024 May 03.
Article
in En
| MEDLINE
| ID: mdl-38701281
ABSTRACT
Neutropenic fever in adults undergoing chemotherapy for cancer treatment is a medical emergency and has been the focus of numerous studies. However, there is a paucity of data about non-chemotherapy induced neutropenic fever (non-CINF). We retrospectively reviewed 383 adults with neutropenic fever hospitalized at one academic medical center between October 2015 and September 2020 to characterize the frequency, causes, and outcomes of non-CINF. Twenty-six percent of cases of neutropenic fever were non-chemotherapy induced. Among these, the major causes of neutropenia were hematologic malignancy, infection, and rheumatologic disease, and the major causes of fever were infections. Patients with non-CINF had a higher 30-day mortality than those with chemotherapy induced neutropenic fever (25% vs 13%, Pâ
=â
.01). Non-CINF constitutedâ
>â
25% of neutropenic fever events in hospitalized adults and was associated with a high mortality rate.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Fever
/
Hospitalization
/
Neutropenia
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Medicine (Baltimore)
Year:
2024
Document type:
Article
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA