Contrast-enhanced ultrasound for differentiating benign from malignant focal solid renal lesions in pediatric patients.
Sci Rep
; 14(1): 11409, 2024 05 18.
Article
in En
| MEDLINE
| ID: mdl-38762673
ABSTRACT
The contrast-enhanced ultrasound (CEUS) has been mainly applied to adults to differentiate benign and malignant renal lesions, however, the characteristics of CEUS in pediatric has not been as well studied as in adults. In the present work, the eligible pediatric patients who underwent renal CEUS between March 2016 and February 2023 were retrospectively analyzed. It included 20 lesions (median diameter, 8.4 cm; range, 1.8-18.0 cm) from 20 patients (median age, 28.0 months; range, 3.0-212.0 months; 9 boys) in malignant group and 5 lesions (median diameter, 3.8 cm; range, 1.3-7.5 cm) from 5 patients (median age, 25.0 months; range, 0.7-216.0 months; 2 boys) in benign group. The diagnostic performance was assessed. Nonparametric and Chi-square tests were performed. With hyperenhancement plus wash-out, CEUS showed a sensitivity of 95.0% [95% confidence interval (CI) 75.1%, 99.9%], a specificity of 80.0% (CI 28.4%, 99.5%), a positive predictive value of 95.0% (CI 75.1%, 99.9%) and a negative predictive value of 80.0% (CI 28.4%, 99.5%). It suggested that CEUS is a valuable technique for identifying between malignant and benign renal lesions in children.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ultrasonography
/
Contrast Media
/
Kidney Neoplasms
Limits:
Adolescent
/
Child
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Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Sci Rep
Year:
2024
Document type:
Article
Country of publication:
United kingdom