Erythrocyte membrane-camouflaged mesoporous silica composite nanoparticles for loading and controlled release of the hepatoprotective agent silibinin: A-synthesis and physicochemical characterization.

Tayebi Khorrami, Vahid; Raee, Mohammad Javad; Abolmaali, Samira Sadat; Abedanzadeh, Mozhgan; Shafiee, Mina; Tamaddon, Ali Mohammad

Tayebi Khorrami, Vahid; Raee, Mohammad Javad; Abolmaali, Samira Sadat; Abedanzadeh, Mozhgan; Shafiee, Mina; Tamaddon, Ali Mohammad.

Affiliation

Tayebi Khorrami V; Center for Nanotechnology in Drug Delivery, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.
Raee MJ; Center for Nanotechnology in Drug Delivery, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.
Abolmaali SS; Student Research Committee, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.
Abedanzadeh M; Center for Nanotechnology in Drug Delivery, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.
Shafiee M; Department of Pharmaceutical Nanotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.
Tamaddon AM; Department of Pharmaceutical Nanotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.

J Pharm Pharmacol ; 76(8): 995-1005, 2024 Aug 02.

Article in En | MEDLINE | ID: mdl-38762907

Subject(s)

Delayed-Action Preparations; Erythrocyte Membrane; Nanoparticles; Silicon Dioxide; Silybin; Silybin/pharmacology; Silybin/administration & dosage; Silybin/chemistry; Silicon Dioxide/chemistry; Erythrocyte Membrane/drug effects; Protective Agents/pharmacology; Protective Agents/administration & dosage; Drug Liberation; Antioxidants/administration & dosage; Antioxidants/pharmacology; Drug Carriers/chemistry; Silymarin/administration & dosage; Silymarin/pharmacology; Silymarin/chemistry; Silymarin/pharmacokinetics; Porosity; Liver/metabolism; Liver/drug effects; Silybum marianum/chemistry; Humans

Key words

cell membrane; drug delivery; liver fibrosis; mesoporous silica; red blood cell; silibinin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Silicon Dioxide / Delayed-Action Preparations / Erythrocyte Membrane / Nanoparticles / Silybin Limits: Humans Language: En Journal: J Pharm Pharmacol Year: 2024 Document type: Article Affiliation country: Iran Country of publication: United kingdom

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