The effect of eight weeks combined training with omega-3 supplementation on the levels of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in older women.
Clin Nutr ESPEN
; 61: 151-157, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38777428
ABSTRACT
BACKGROUND:
Elevated levels of ICAM-1 and VCAM-1 are significant risk factors for cardiovascular diseases. Conversely, the regulatory roles of physical activity and omega-3 supplementation in these factors have been reported. The primary aim of the present research was to investigate the impact of an eight-week combined (resistance-endurance) accompanied by omega-3 supplementation on ICAM-1 and VCAM-1 levels in elderly women.METHODS:
Forty elderly women, averaging 66.7 ± 4.13 years, were randomly assigned to four groups placebo, omega-3 supplement, training, and training + omega-3. The combined exercise training program was implemented for eight weeks, three sessions per week. Aerobic training included 20 min of running at 60-70% of the reserve heart rate, while resistance training involved exercises at 70% of 1RM with 10 repetitions per exercise for two sets. The omega-3 and training + omega-3 groups consumed 2000 mg of omega-3 daily. Blood samples were collected 48 h after the last combined exercise training or omega-3 consumption, and the measured variables were analyzed using analysis of covariance test and SPSS-24 software.RESULTS:
ICAM-1 and VCAM-1 levels significantly decreased in the training and training + omega-3 groups (p < 0.001). The decrease in ICAM-1 within the training + omega-3 group was also significant compared to the training group (p = 0.024). Additionally, a significant reduction in insulin resistance and body fat percentage was observed in both the training and training + omega-3 groups (p < 0.001).CONCLUSION:
The present study's results indicate that omega-3 supplementation can enhance the effectiveness of combined training in regulating cardiovascular risk factors.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Fatty Acids, Omega-3
/
Intercellular Adhesion Molecule-1
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Vascular Cell Adhesion Molecule-1
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Dietary Supplements
/
Resistance Training
Limits:
Aged
/
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Clin Nutr ESPEN
Year:
2024
Document type:
Article
Affiliation country:
Iran
Country of publication:
United kingdom