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Influence of antimicrobial peptides on the bacterial membrane curvature and vice versa.
Cardoso, Marlon H; de la Fuente-Nunez, Cesar; Santos, Nuno C; Zasloff, Michael A; Franco, Octávio L.
Affiliation
  • Cardoso MH; S-inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, - MS, Brazil; Centro de Análises Proteômicas e Bioquímicas, Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília, - DF, Brazil; Instituto de Biociên
  • de la Fuente-Nunez C; Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Departments of Bioengineering and Chemical and Biomolecular
  • Santos NC; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
  • Zasloff MA; Georgetown University School of Medicine, MedStar Georgetown Transplant Institute, Washington, DC, USA.
  • Franco OL; S-inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, - MS, Brazil; Centro de Análises Proteômicas e Bioquímicas, Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília, - DF, Brazil.
Trends Microbiol ; 32(7): 624-627, 2024 Jul.
Article in En | MEDLINE | ID: mdl-38777700
ABSTRACT
Many factors contribute to bacterial membrane stabilization, including steric effects between lipids, membrane spontaneous curvature, and the difference in the number of neighboring molecules. This forum provides an overview of the physicochemical properties associated with membrane curvature and how this parameter can be tuned to design more effective antimicrobial peptides.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Cell Membrane / Antimicrobial Peptides Language: En Journal: Trends Microbiol Journal subject: MICROBIOLOGIA Year: 2024 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Cell Membrane / Antimicrobial Peptides Language: En Journal: Trends Microbiol Journal subject: MICROBIOLOGIA Year: 2024 Document type: Article