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Influence of E-cadherin deficiency on the dendrite morphology of Langerhans cells.
Dorn, Britta; Ruhland, Cindy; Kunz, Stefanie; Martin, Stefan F; Jakob, Thilo.
Affiliation
  • Dorn B; Department of Dermatology and Allergology, Experimental Dermatology and Allergy Research Group, University Medical Center Gießen, Justus Liebig University Gießen, Gießen, Germany.
  • Ruhland C; Department of Dermatology and Allergology, Experimental Dermatology and Allergy Research Group, University Medical Center Gießen, Justus Liebig University Gießen, Gießen, Germany.
  • Kunz S; Allergy Research Group, Department of Dermatology, Medical Center, University of Freiburg, Freiburg, Germany.
  • Martin SF; Allergy Research Group, Department of Dermatology, Medical Center, University of Freiburg, Freiburg, Germany.
  • Jakob T; Department of Dermatology and Allergology, Experimental Dermatology and Allergy Research Group, University Medical Center Gießen, Justus Liebig University Gießen, Gießen, Germany.
Eur J Immunol ; : e2350797, 2024 May 22.
Article in En | MEDLINE | ID: mdl-38778497
ABSTRACT
The expression of E-cadherin on Langerhans cells (LC) is required for adequate dendrite intercalation between epidermal keratinocytes. Upon disruption of epidermal homeostasis by tape stripping, E-cadherin competent LC extend dendrites reaching up to the epidermal surface, while E-cad deficient LC lack this ability.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Eur J Immunol Year: 2024 Document type: Article Affiliation country: Germany Country of publication: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Eur J Immunol Year: 2024 Document type: Article Affiliation country: Germany Country of publication: Germany