Optimal antibiotics duration following surgical management of septic olecranon bursitis: a 12-year retrospective analysis.
J Bone Jt Infect
; 9(2): 107-115, 2024.
Article
in En
| MEDLINE
| ID: mdl-38779581
ABSTRACT
Introduction:
The absence of a standardized postoperative antibiotic treatment approach for patients with surgically treated septic bursitis results in disparate practices.Methods:
We retrospectively reviewed charts of adult patients with surgically treated septic olecranon bursitis at Mayo Clinic sites between 1 January 2000 and 20 August 2022, focusing on their clinical presentation, diagnostics, management, postoperative antibiotic use, and outcomes.Results:
A total of 91 surgically treated patients were identified during the study period. Staphylococcus aureus was the most common pathogen (64â¯%). Following surgery, 92â¯% (84 of 91 patients) received systemic antibiotics. Excluding initial presentations of bacteremia or osteomyelitis (n=5), the median duration of postoperative antibiotics was 21â¯d (interquartile range, IQR 14-29). Postoperative complications were observed in 23â¯% (21 of 91) of patients, while cure was achieved in 87â¯% (79 of 91). Active smokers had 4.53 times greater odds of clinical failure compared with nonsmokers (95â¯% confidence interval, 95â¯% CI 1.04-20.50; p=0.026). The highest odds of clinical failure were noted in cases without postoperative antibiotic administration (odds ratio, OR 7.4). Conversely, each additional day of antibiotic treatment, up to 21â¯d, was associated with a progressive decrease in the odds of clinical failure (OR 1 at 21â¯d).Conclusion:
The optimal duration of antibiotics postoperatively in this study was 21â¯d, which was associated with a 7.4-fold reduction in the odds clinical failure compared with cases without postoperative antibiotics. Further validation through a randomized controlled trial is needed.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Bone Jt Infect
Year:
2024
Document type:
Article
Affiliation country:
United States