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Enhanced Insights into Frontal Fibrosing Alopecia: Advancements in Pathogenesis Understanding and Management Strategies.
Starace, Michela; Cedirian, Stephano; Rapparini, Luca; Quadrelli, Federico; Pampaloni, Francesca; Bruni, Francesca; Piraccini, Bianca M.
Affiliation
  • Starace M; Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138, Bologna, Italy.
  • Cedirian S; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
  • Rapparini L; Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138, Bologna, Italy. stephano.cedirian96@gmail.com.
  • Quadrelli F; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy. stephano.cedirian96@gmail.com.
  • Pampaloni F; Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138, Bologna, Italy.
  • Bruni F; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
  • Piraccini BM; Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138, Bologna, Italy.
Dermatol Ther (Heidelb) ; 14(6): 1457-1477, 2024 Jun.
Article in En | MEDLINE | ID: mdl-38822213
ABSTRACT
Frontal fibrosing alopecia (FFA) represents a distinctive form of primary lymphocytic scarring alopecia characterized by fronto-temporal hair recession and eyebrow hair loss. While predominantly affecting postmenopausal women, FFA also occurs in women of reproductive age and men, with variations observed across different ethnic groups. Genetic predisposition, environmental factors and inflammatory pathways contribute to its pathogenesis, with evolving diagnostic criteria enhancing accuracy. FFA treatment lacks standardization, encompassing topical, systemic and physical therapies, while hair transplantation remains a temporary solution. This article reviews the current understanding of FFA, aiming to provide clinicians with updated insights for its management.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Dermatol Ther (Heidelb) Year: 2024 Document type: Article Affiliation country: Italy Country of publication: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Dermatol Ther (Heidelb) Year: 2024 Document type: Article Affiliation country: Italy Country of publication: Switzerland