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Exacerbation-like events in the 12 months prior to identification of chronic respiratory conditions in a primary care population.
Quezada, Wilson A; Angulo, Daniela; Murray, Susan; Joo, Min; Han, Meilan; Make, Barry; Thomashow, Byron; Mannino, David; Tapp, Hazel; Martinez, Fernando; Yawn, Barbara P.
Affiliation
  • Quezada WA; Columbia University School of Medicine, New York, NY, USA.
  • Angulo D; University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Murray S; University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Joo M; University of Illinois Chicago, Chicago, IL, USA.
  • Han M; University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Make B; National Jewish Health Center, Denver, CO, USA.
  • Thomashow B; Columbia University School of Medicine, New York, NY, USA.
  • Mannino D; University of Kentucky School of Medicine, Lexington, KY, USA.
  • Tapp H; Atrium Health, Charlotte, NC, USA.
  • Martinez F; Cornell-Weil School of Medicine, New York, NY, USA.
  • Yawn BP; University of Minnesota School of Medicine, Minneapolis, MN, USA. Electronic address: Byawn47@gmail.com.
Respir Med ; 231: 107695, 2024 Sep.
Article in En | MEDLINE | ID: mdl-38848821
ABSTRACT
Initial chronic obstructive lung disease (COPD) pharmacotherapy is based on symptom burden and exacerbation history. Inclusion of inhaled cortico-steroids (ICS) is recommended only for those with a history of exacerbations. This brief report highlights that among individuals with previously unrecognized COPD about 1 in 5 have one or more exacerbation-like events and about 1 in 10 have two or more events in the prior 12 months whether or not they self-report concomitant asthma. Closer attention to prior exacerbation-like event history might lead to more guideline concordant care. In addition, there are two other groups that have impaired but non-obstructive spirometry, some with significant respiratory symptom burden who have frequencies of exacerbation-like events similar to those meeting COPD spirometry criteria. To date we have little guidance for treatment of these individuals.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Primary Health Care / Asthma / Spirometry / Disease Progression / Pulmonary Disease, Chronic Obstructive Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Respir Med Year: 2024 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Primary Health Care / Asthma / Spirometry / Disease Progression / Pulmonary Disease, Chronic Obstructive Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Respir Med Year: 2024 Document type: Article Affiliation country: United States Country of publication: United kingdom