Antimicrobial resistance among pregnant women with urinary tract infections is on rise: Findings from meta-analysis of observational studies.
J Infect Public Health
; 17(7): 102467, 2024 Jul.
Article
in En
| MEDLINE
| ID: mdl-38850585
ABSTRACT
Pregnant women have a higher risk of urinary tract infections (UTIs) compared to non-pregnant women, making antibiotics necessary for treatment. However, prescribing antibiotics without culture and sensitivity tests may contribute to antimicrobial resistance. A meta-analysis using R was conducted to determine the prevalence of antibiotic resistance patterns in UTIs among pregnant women. We identified observational studies published in the last 10 years and used a random effects model to calculate the pooled prevalence. The prevalence of Gram-negative organisms causing UTIs in pregnant women was 67 %, while Gram-positive organisms were 22 %. The burden of Gram-positive organisms exhibiting antimicrobial resistance was very high at 95 %, primarily to ampicillin. The most common Gram-negative organisms exhibiting antimicrobial resistance were E. coli, Klebsiella, and Pseudomonas aeruginosa, while the most common Gram-positive organisms resistant to antibiotics were Staphylococcus aureus and coagulase-negative Staphylococcus. Sensitivity and culture testing are recommended for effective treatment in pregnant women with UTIs.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pregnancy Complications, Infectious
/
Urinary Tract Infections
/
Drug Resistance, Bacterial
/
Observational Studies as Topic
/
Anti-Bacterial Agents
Limits:
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
J Infect Public Health
Journal subject:
DOENCAS TRANSMISSIVEIS
/
SAUDE PUBLICA
Year:
2024
Document type:
Article
Country of publication:
United kingdom