Your browser doesn't support javascript.
loading
Bioinspired cellular membrane-derived vesicles for mRNA delivery.
Xu, Xiao; Xu, Limei; Wang, Jingzhi; Wen, Caining; Xia, Jiang; Zhang, Yuanmin; Liang, Yujie.
Affiliation
  • Xu X; Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.
  • Xu L; Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.
  • Wang J; Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.
  • Wen C; Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.
  • Xia J; Department of Chemistry, The Chinese University of Hong Kong, Hong Kong, China.
  • Zhang Y; Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.
  • Liang Y; College of Rehabilitation Medicine, Jining Medical University, Jining, China.
Theranostics ; 14(8): 3246-3266, 2024.
Article in En | MEDLINE | ID: mdl-38855184
ABSTRACT
The rapid advancement of mRNA as vaccines and therapeutic agents in the biomedical field has sparked hope in the fight against untreatable diseases. Successful clinical application of mRNA therapeutics largely depends on the carriers. Recently, a new and exciting focus has emerged on natural cell-derived vesicles. These nanovesicles offer many functions, including enhanced drug delivery capabilities and immune evasion, thereby presenting a unique and promising platform for the effective and safe delivery of mRNA therapeutics. In this study, we summarize the characteristics and properties of biomimetic delivery systems for mRNA therapeutics. In particular, we discuss the unique features of cellular membrane-derived vesicles (CDVs) and the combination of synthetic nanovesicles with CDVs.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Messenger / Drug Delivery Systems Limits: Animals / Humans Language: En Journal: Theranostics Year: 2024 Document type: Article Affiliation country: China
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Messenger / Drug Delivery Systems Limits: Animals / Humans Language: En Journal: Theranostics Year: 2024 Document type: Article Affiliation country: China