Electrodiagnostic tests of the visual pathway and applications in neuro-ophthalmology.
Eye (Lond)
; 38(12): 2392-2405, 2024 Aug.
Article
in En
| MEDLINE
| ID: mdl-38862643
ABSTRACT
This article describes the main visual electrodiagnostic tests relevant to neuro-ophthalmology practice, including the visual evoked potential (VEP), and the full-field, pattern and multifocal electroretinograms (ffERG; PERG; mfERG). The principles of electrophysiological interpretation are illustrated with reference to acquired and inherited optic neuropathies, and retinal disorders that may masquerade as optic neuropathy, including ffERG and PERG findings in cone and macular dystrophies, paraneoplastic and vascular retinopathies. Complementary VEP and PERG recordings are illustrated in demyelinating, ischaemic, nutritional (B12), and toxic (mercury, cobalt, and ethambutol-related) optic neuropathies and inherited disorders affecting mitochondrial function such as Leber hereditary optic neuropathy and dominant optic atrophy. The value of comprehensive electrophysiological phenotyping in syndromic diseases is highlighted in cases of SSBP1-related disease and ROSAH (Retinal dystrophy, Optic nerve oedema, Splenomegaly, Anhidrosis and Headache). The review highlights the value of different electrophysiological techniques, for the purposes of differential diagnosis and objective functional phenotyping.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Visual Pathways
/
Optic Nerve Diseases
/
Electroretinography
/
Evoked Potentials, Visual
Limits:
Humans
Language:
En
Journal:
Eye (Lond)
Journal subject:
OFTALMOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
United kingdom