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Role of Hydrophobic Modification in Spermine-Based Poly(ß-amino ester)s for siRNA Delivery and Their Spray-Dried Powders for Inhalation and Improved Storage.
Jin, Yao; Wang, Xiaoxuan; Kromer, Adrian P E; Müller, Joschka T; Zimmermann, Christoph; Xu, Zehua; Hartschuh, Achim; Adams, Friederike; Merkel, Olivia M.
Affiliation
  • Jin Y; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
  • Wang X; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
  • Kromer APE; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
  • Müller JT; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
  • Zimmermann C; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
  • Xu Z; Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
  • Hartschuh A; Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
  • Adams F; Center for Nanoscience (CeNS), Ludwig-Maximilians-Universität München, 80799 München, Germany.
  • Merkel OM; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 Munich, Germany.
Biomacromolecules ; 25(7): 4177-4191, 2024 Jul 08.
Article in En | MEDLINE | ID: mdl-38866384
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spermine / RNA, Small Interfering / Hydrophobic and Hydrophilic Interactions Limits: Humans Language: En Journal: Biomacromolecules Journal subject: BIOLOGIA MOLECULAR Year: 2024 Document type: Article Affiliation country: Germany Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spermine / RNA, Small Interfering / Hydrophobic and Hydrophilic Interactions Limits: Humans Language: En Journal: Biomacromolecules Journal subject: BIOLOGIA MOLECULAR Year: 2024 Document type: Article Affiliation country: Germany Country of publication: United States