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Hepatitis B-CpG Vaccine Series for Healthcare Workers Who Are Hepatitis B Vaccine Nonresponders.
Russ, Rachel K; Vandehei, Haley M; Golovkina, Maria I; Mogallapalli, Harshitha; Caldera, Freddy; Hayney, Mary S.
Affiliation
  • Russ RK; School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Vandehei HM; Employee Health Services, UW Health, Madison, Wisconsin, USA.
  • Golovkina MI; School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Mogallapalli H; Department of Medicine, Division of Gastroenterology and Hepatology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.
  • Caldera F; Department of Medicine, Division of Gastroenterology and Hepatology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.
  • Hayney MS; School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Clin Infect Dis ; 79(2): 562-563, 2024 Aug 16.
Article in En | MEDLINE | ID: mdl-38881506
ABSTRACT
This prospective study enrolled healthcare workers (HCWs) who were nonresponders following at least 5 doses of aluminum-adjuvanted hepatitis B vaccine who received the 2-dose Heplisav-B (HepB-CpG) (Dynavax Technologies Corporation, Emeryville, CA) series. After 2 doses of HepB-CpG, 43/47 (91%) participants, and with 1 dose, 41/49 (84%) responded. HepB-CpG could be the preferred vaccine in HCW nonresponders. Clinical Trials Registration. Clinicaltrials.gov NCT04456504.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Health Personnel / Hepatitis B Vaccines / Hepatitis B Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2024 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Health Personnel / Hepatitis B Vaccines / Hepatitis B Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2024 Document type: Article Affiliation country: United States