Blood Substitutes with Gas Transfer Function.
Bull Exp Biol Med
; 176(6): 709-715, 2024 Apr.
Article
in En
| MEDLINE
| ID: mdl-38888647
ABSTRACT
The review presents the results of the blood substitute development based on perfluororganic compounds (PFC). The limitations of PFC due to which their further development was suspended are described. The presented data allows us to imagine a possible way to create optimal drugs based on PFC. Chemically inactive perfluorocomponents should be used - perfluorinated hydrocarbons and tertiary perfluorinated amines. However, in order to emulsify and stabilize the emulsion, other types of effective and chemically indifferent surfactants that do not interact with oxygen and other components of the drug are needed.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Blood Substitutes
/
Fluorocarbons
Limits:
Animals
/
Humans
Language:
En
Journal:
Bull Exp Biol Med
Year:
2024
Document type:
Article
Affiliation country:
RUSSIA
Country of publication:
United States