TSAT: Efficient evaluation software for NGS data of phage/mirror-image phage display selections.
Biophys Rep (N Y)
; 4(3): 100166, 2024 Jun 21.
Article
in En
| MEDLINE
| ID: mdl-38909902
ABSTRACT
Phage display and mirror-image phage display are commonly used techniques for the identification of binders that are specific to predefined targets. Recent studies demonstrated the effectiveness of next-generation sequencing (NGS) by increasing the amount of information extracted from selections. This allows for a better analysis and increases the possibility to select effective binders. A potential downside to NGS analysis of phage display selections is the increased workload that is needed to analyze the obtained information. Here, we report on the development of TSAT (target-specific analysis tool), software for user-friendly and efficient analysis of peptide sequence data from NGS of phage display selections.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Biophys Rep (N Y)
Year:
2024
Document type:
Article
Affiliation country:
Germany