A patient with anti-f in India identified by extensive immunohematologic workup.
Immunohematology
; 40(2): 54-57, 2024 Jun 01.
Article
in En
| MEDLINE
| ID: mdl-38910446
ABSTRACT
Anti-f is produced by exposure to the compound antigen ce (f) on red blood cells (RBCs), expressed when both c and e are present on the same protein (cis position). Although anti-f was discovered in 1953, there are few cases reported worldwide because the presence of anti-f is often masked by anti-c or anti-e and is not generally found as a single antibody. In the present case, anti-f was identified by using three-cell screening and 11-cell identification panels. The identification of anti-f was further supported by additional testing, including (1) Rh antigen typing; (2) antibody identification panels (enzyme-treated panel [ficin] and an in-house-constructed Rh panel); (3) look-back and phenotyping of donor RBC units, which were responsible for alloimmunization; and (4) molecular testing of the patient's RBCs.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Isoantibodies
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
En
Journal:
Immunohematology
Journal subject:
ALERGIA E IMUNOLOGIA
/
HEMATOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
India
Country of publication:
United States