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Outbreak of Burkholderia cenocepacia in an intensive care unit of a tertiary care hospital identified by pulsed-field gel electrophoresis.
Kumaresan, Mahalakshmi; Manoharan, Meerabai; Sugumar, Madhan; Sistla, Sujatha.
Affiliation
  • Kumaresan M; Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India. Electronic address: mahalakshmik2013@gmail.com.
  • Manoharan M; Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India. Electronic address: meerammb@yahoo.com.
  • Sugumar M; Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India. Electronic address: micromadhan@gmail.com.
  • Sistla S; Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India. Electronic address: sujathasistla@gmail.com.
Indian J Med Microbiol ; 50: 100655, 2024.
Article in En | MEDLINE | ID: mdl-38914312
ABSTRACT
Nosocomial outbreaks of Burkholderia cepacia complex, transmitted through contaminated medical surfaces or equipment have been reported. Pulsed-field Gel Electrophoresis (PFGE) is recognized as the "gold standard" for molecular subtyping, yet studies on clonal relationships in India are limited. PFGE was used to study the clonal relationships of 22 isolates of Burkholderia cenocepacia from 12 patients admitted to a critical care unit during 2 months (November and December 2021). PFGE revealed three different profiles with 15 isolates belonging to a single cluster suggesting a common source within the hospital, emphasizing the need for preventive measures to control B. cenocepacia transmission.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cross Infection / Disease Outbreaks / Electrophoresis, Gel, Pulsed-Field / Burkholderia Infections / Burkholderia cenocepacia / Tertiary Care Centers / Intensive Care Units Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Indian J Med Microbiol Journal subject: MICROBIOLOGIA Year: 2024 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cross Infection / Disease Outbreaks / Electrophoresis, Gel, Pulsed-Field / Burkholderia Infections / Burkholderia cenocepacia / Tertiary Care Centers / Intensive Care Units Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Indian J Med Microbiol Journal subject: MICROBIOLOGIA Year: 2024 Document type: Article Country of publication: United States