Stability of ascorbic acid in human aqueous humor.
BMC Res Notes
; 17(1): 179, 2024 Jun 26.
Article
in En
| MEDLINE
| ID: mdl-38926714
ABSTRACT
OBJECTIVE:
The stability of ascorbic acid (AA) in the human aqueous humor (AqH) remains unclear. This study aimed to investigate the stability of AqH AA under varying conditions (27, 4, - 20, and - 80 °C) without acidification.RESULTS:
Rapid AA degradation occurred at 27 °C. At 4 °C, a significant 12.2% degradation was observed after 24 h. Storage at - 20 °C resulted in a notable 37.5% degradation after 28 days, whereas storage at - 80 °C resulted in 10.7% degradation after 28 days. Unacidified AqH samples recorded early decomposition at 27 °C and 4 °C. In conclusion, it is recommended to conduct measurements within 28 days for samples stored at - 80 °C.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aqueous Humor
/
Ascorbic Acid
Limits:
Humans
Language:
En
Journal:
BMC Res Notes
Year:
2024
Document type:
Article
Affiliation country:
Japan