Effects of Staphylococcus aureus on stem cells and potential targeted treatment of inflammatory disorders.
Stem Cell Res Ther
; 15(1): 187, 2024 Jun 27.
Article
in En
| MEDLINE
| ID: mdl-38937829
ABSTRACT
Due to the advanced studies on stem cells in developmental biology, the roles of stem cells in the body and their phenotypes in related diseases have not been covered clearly. Meanwhile, with the intensive research on the mechanisms of stem cells in regulating various diseases, stem cell therapy is increasingly being attention because of its effectiveness and safety. As one of the most widely used stem cell in stem cell therapies, hematopoietic stem cell transplantation shows huge advantage in treatment of leukemia and other blood-malignant diseases. Besides, due to the effect of anti-inflammatory and immunomodulatory, mesenchymal stem cells could be a potential therapeutic strategy for variety infectious diseases. In this review, we summarized the effects of Staphylococcus aureus (S. aureus) and its components on different types of adult stem cells and their downstream signaling pathways. Also, we reviewed the roles of different kinds of stem cells in various disease models caused by S. aureus, providing new insights for applying stem cell therapy to treat infectious diseases.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Staphylococcus aureus
Limits:
Animals
/
Humans
Language:
En
Journal:
Stem Cell Res Ther
/
Stem cell res. ther
/
Stem cell research & therapy
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
United kingdom