Current Applications of Colorectal Cancer Organoids: A Review.
J Gastrointestin Liver Dis
; 33(2): 269-277, 2024 Jun 29.
Article
in En
| MEDLINE
| ID: mdl-38944855
ABSTRACT
Colorectal cancer is a prevalent malignancy, with advanced and metastatic forms exhibiting poor treatment outcomes and high relapse rates. To enhance patient outcomes, a comprehensive understanding of the pathophysiological processes and the development of targeted therapies are imperative. The high heterogeneity of colorectal cancer demands precise and personalized treatment strategies. Colorectal cancer organoids, a three-dimensional in vitro model, have emerged as a valuable tool for replicating tumor biology and exhibit promise in scientific research, disease modeling, drug screening, and personalized medicine. In this review, we present an overview of colorectal cancer organoids and explore their applications in research and personalized medicine, while also discussing potential future developments in this field.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Colorectal Neoplasms
/
Organoids
/
Precision Medicine
Limits:
Animals
/
Humans
Language:
En
Journal:
J Gastrointestin Liver Dis
Journal subject:
GASTROENTEROLOGIA
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
Romania