One mechanism of sudden sensorineural hearing loss after sildenafil and sexual activity.
Int J Audiol
; : 1-4, 2024 Jul 01.
Article
in En
| MEDLINE
| ID: mdl-38949065
ABSTRACT
OBJECTIVES:
A case of sudden sensorineural hearing loss following use of sildenafil was examined in detail over a period of three days from first report to recovery.DESIGN:
Case study. The subject presented with sudden sensorineural hearing loss and diplacusis a day after onset. Testing involved detailed interview, standard audiometry, detailed inter-octave audiometry, and measurement of detailed psychophysical frequency tuning curves during a two day recovery period. STUDY SAMPLE One male aged in his thirties with otherwise normal hearing.RESULTS:
Although standard audiometry was within normal limits, detailed inter-octave audiometry and psychophysical frequency tuning curves were consistent with a punctate unilateral intra-cochlear lesion that resolved over a period of three days.CONCLUSIONS:
This is the first report of such a frequency-specific audiometric shift and diplacusis after sildenafil, and is not consistent with previous reports of direct ototoxic pharmacological effects. We propose that the lesion was most likely caused by a cochlear bleed, and may have been due to physical exertion rather than a direct pharmaceutical effect. The study highlights the important role of additional diagnostic testing that can be easily achieved in a clinical setting with minimal equipment.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Int J Audiol
Journal subject:
AUDIOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Australia