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Models of sepsis-induced acute kidney injury.
Dong, Liang; Xie, Yi-Ling; Zhang, Ren-Tao; Hu, Qiong-Ying.
Affiliation
  • Dong L; Department of Critical Care Medicine, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou 318000, Zhejiang, China.
  • Xie YL; Department of Critical Care Medicine, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou 318000, Zhejiang, China.
  • Zhang RT; Department of Critical Care Medicine, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou 318000, Zhejiang, China.
  • Hu QY; Department of Critical Care Medicine, Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou 318000, Zhejiang, China. Electronic address: qiongyinghu@tzc.edu.cn.
Life Sci ; 352: 122873, 2024 Sep 01.
Article in En | MEDLINE | ID: mdl-38950643
ABSTRACT
Sepsis-induced acute kidney injury (S-AKI) is one of the most serious life-threatening complications of sepsis. The pathogenesis of S-AKI is complex and there is no effective specific treatment. Therefore, it is crucial to choose suitable preclinical models that are highly similar to human S-AKI to study the pathogenesis and drug treatment. In this review, we summarized recent advances in the development models of S-AKI, providing reference for the reasonable selection of experimental models as basic research and drug development of S-AKI.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sepsis / Disease Models, Animal / Acute Kidney Injury Limits: Animals / Humans Language: En Journal: Life Sci Year: 2024 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sepsis / Disease Models, Animal / Acute Kidney Injury Limits: Animals / Humans Language: En Journal: Life Sci Year: 2024 Document type: Article Affiliation country: China