Your browser doesn't support javascript.
loading
Next-Generation Vaccine Development with Nanomaterials: Recent Advances, Possibilities, and Challenges.
Shetty, Shamitha; Alvarado, Pablo Cordero; Pettie, Deleah; Collier, Joel H.
Affiliation
  • Shetty S; Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA; email: shamitha.shetty@duke.edu, p.cordero@duke.edu, deleah.pettie@duke.edu, joel.collier@duke.edu.
  • Alvarado PC; Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA; email: shamitha.shetty@duke.edu, p.cordero@duke.edu, deleah.pettie@duke.edu, joel.collier@duke.edu.
  • Pettie D; Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA; email: shamitha.shetty@duke.edu, p.cordero@duke.edu, deleah.pettie@duke.edu, joel.collier@duke.edu.
  • Collier JH; Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA; email: shamitha.shetty@duke.edu, p.cordero@duke.edu, deleah.pettie@duke.edu, joel.collier@duke.edu.
Annu Rev Biomed Eng ; 26(1): 273-306, 2024 Jul.
Article in En | MEDLINE | ID: mdl-38959389
ABSTRACT
Nanomaterials are becoming important tools for vaccine development owing to their tunable and adaptable nature. Unique properties of nanomaterials afford opportunities to modulate trafficking through various tissues, complement or augment adjuvant activities, and specify antigen valency and display. This versatility has enabled recent work designing nanomaterial vaccines for a broad range of diseases, including cancer, inflammatory diseases, and various infectious diseases. Recent successes of nanoparticle vaccines during the coronavirus disease 2019 (COVID-19) pandemic have fueled enthusiasm further. In this review, the most recent developments in nanovaccines for infectious disease, cancer, inflammatory diseases, allergic diseases, and nanoadjuvants are summarized. Additionally, challenges and opportunities for clinical translation of this unique class of materials are discussed.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nanostructures / SARS-CoV-2 / COVID-19 / Vaccine Development Limits: Animals / Humans Language: En Journal: Annu Rev Biomed Eng Journal subject: ENGENHARIA BIOMEDICA Year: 2024 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nanostructures / SARS-CoV-2 / COVID-19 / Vaccine Development Limits: Animals / Humans Language: En Journal: Annu Rev Biomed Eng Journal subject: ENGENHARIA BIOMEDICA Year: 2024 Document type: Article Country of publication: United States