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An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus an aminoglycoside + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial-an update to the published protocol.
Randremanana, Rindra Vatosoa; Raberahona, Mihaja; de Dieu Randria, Mamy Jean; Bourner, Josephine; Zadonirina, Gabriella; Razananaivo, Hanitra; Mayouya-Gamana, Théodora; Mangahasimbola, Reziky; Pesonel, Elise; Gillesen, Annelies; Rajerison, Minoarisoa; Andrianaivoarimanana, Voahangy; Edwards, Tansy; Horby, Peter; Olliaro, Piero.
Affiliation
  • Randremanana RV; Institut Pasteur de Madagascar, Antananarivo, Madagascar.
  • Raberahona M; Centre d'Infectiologie Charles Mérieux, University of Antananarivo, Antananarivo, Madagascar.
  • de Dieu Randria MJ; Department of Infectious Diseases, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar.
  • Bourner J; Department of Infectious Diseases, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar.
  • Zadonirina G; Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar.
  • Razananaivo H; ISARIC, Pandemic Sciences Institute, University of Oxford, Oxford, UK. josephine.bourner@ndm.ox.ac.uk.
  • Mayouya-Gamana T; Institut Pasteur de Madagascar, Antananarivo, Madagascar.
  • Mangahasimbola R; Institut Pasteur de Madagascar, Antananarivo, Madagascar.
  • Pesonel E; Institut Pasteur de Madagascar, Antananarivo, Madagascar.
  • Gillesen A; Institut Pasteur de Madagascar, Antananarivo, Madagascar.
  • Rajerison M; ISARIC, Pandemic Sciences Institute, University of Oxford, Oxford, UK.
  • Andrianaivoarimanana V; ISARIC, Pandemic Sciences Institute, University of Oxford, Oxford, UK.
  • Edwards T; Institut Pasteur de Madagascar, Antananarivo, Madagascar.
  • Horby P; Institut Pasteur de Madagascar, Antananarivo, Madagascar.
  • Olliaro P; London School of Hygiene and Tropical Medicine, London, UK.
Trials ; 25(1): 457, 2024 Jul 05.
Article in En | MEDLINE | ID: mdl-38970065
ABSTRACT
This article reports an update to the protocol of the IMASOY trial, which was prospectively registered on clinicaltrials.gov (NCT04110340) in October 2019.
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ciprofloxacin / Anti-Bacterial Agents Limits: Animals / Humans Language: En Journal: Trials / Trials (Online) Journal subject: MEDICINA / TERAPEUTICA Year: 2024 Document type: Article Affiliation country: Madagascar Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ciprofloxacin / Anti-Bacterial Agents Limits: Animals / Humans Language: En Journal: Trials / Trials (Online) Journal subject: MEDICINA / TERAPEUTICA Year: 2024 Document type: Article Affiliation country: Madagascar Country of publication: United kingdom